Knock-down of both eIF4E1 and eIF4E2 genes confers broad-spectrum resistance against potyviruses in tomato.
BACKGROUND: The eukaryotic translation initiation factor eIF4E plays a key role in plant-potyvirus interactions.eIF4E belongs to a small multigenic family and three genes, eIF4E1, eIF4E2 and eIF(iso)4E, have been identified in tomato.It has been demonstrated that eIF4E-mediated natural recessive resistances against potyviruses result from non-synon